Environmental effects on ship hydrodynamics during inland waterway transport are investigated using both CFD (Computational Fluid Dynamics) and towing tank experiments. Three important scenes, the confinement effect of the waterway, head-on encounter and ship-bridge pier interactions are studied. The testing conditions cover a wide range, including various channel dimensions, water depths, ship draughts and speeds. The ship resistance, wave pattern, Kelvin angle and wave elevations are investigated as functions of these parameters.