This chapter re-examines some of the key elements that structure today's so-called “integrated design” approaches and offers perspectives for the transfer and adoption of best practices, from the manufacturing industry to the construction and building sector. It addresses the concepts of digital mock-up, product lifecycle management, the role of product modeling and associated standards, collaborative and multidisciplinary design and certain developments in practices related to the deployment of systems engineering, as well as the beginnings of the application of “agility” principles to project management. The digital mock-up includes computer-aided design files or 3D models but is not limited to them. The chapter discusses the product ontologies that began appearing within mechanical engineering community in the 2010s, and which are now widely employed in scientific works. Ontologies meet a number of needs concerning the management of data, both information and knowledge, particularly at the semantic level.