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                <term xml:lang="en">High density surface electromyography (HD-sEMG)</term>
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              <p>The purpose of the study is the real time spatial localization of single motor units using simulated Motor Unit Action Potential dictionary from a cylindrical muscle volume conductor model by means of a state-of-the-art curve fitting method. This Curve Fitting Based Minimum Norm Estimation (CFB-MNE) was made possible by using minimum norm estimation methods to solve an underdetermined inverse problem knowing produced HD-sEMG signals. Specific data extracted from the inverse problem of a pre-determined number of simulated motor units were used to create a 3D curve, which can be used as a fitting curve to anticipate the unknown location of motor units. Results show that the proposed algorithms succeeded in accurately localizing motor units with varying noise levels in a fast duration (less than 100 ms). From all the simulations, a mean root mean square error of maximum 1 mm was recorded for the localization of the depth (less than 1 mm) and a negligible error for the angular position (less than 1°). The proposed work is an innovative algorithm that aids in non-invasively localizing motor units within a muscle in real time. Further efforts are planned to manage MUAP superposition and type. Final applications are related to prosthetic control, rehabilitation guidance or aging monitoring.</p>
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